Phenylpropanoids and polyketides
Medchemexpress LLC MTX-531 | 2791417-66-6 | 99.9% | 453.94 | 5 MG
MTX-531 is an oral drug that inhibits EGFR and PI3K isoforms (PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ). It has anti-tumor effects and acts as a weak agonist of PPARγ, which helps mitigate hyperglycemia often induced by PI3K inhibitors. It shows excellent tolerance in mice and has demonstrated concentration-dependent inhibitory effects on EGFR, P13K, and mTOR in CAL-33 cells.
- Inhibits EGFR and PI3K isoforms
- Acts as a weak agonist of PPARγ, alleviating PI3K inhibitor-induced hyperglycemia
- Demonstrates anti-tumor activity in various models
- Administered orally
- Shows excellent tolerance in mice
Medchemexpress LLC Fotagliptin benzoate | 1403496-40-1 | 99.2% | 464.49 g/mol | C24H25FN6O3 | 10MG
Fotagliptin benzoate is the benzoate salt form of fotagliptin, a potent dipeptidyl peptidase-4 (DPP-4) inhibitor used in preclinical research for Type 2 diabetes. The compound is supplied in small research quantities and is characterized for in vitro and in vivo formulations, with documented solubility and storage recommendations to support pharmacology studies.
- CAS 1403496-40-1.
- Molecular formula C24H25FN6O3 and molecular weight 464.49 g/mol.
- Reported DPP-4 inhibitory activity (IC50 ≈ 22.7 nM).
- High solubility in DMSO (100 mg/mL) and reported in vivo formulations with solubility ≥ 2.5 mg/mL.
- Storage: 4°C sealed; in solvent -80°C (6 months) or -20°C (1 month).
- Available in small pack sizes for research use (examples: 1 mg, 5 mg, 10 mg).
Medchemexpress LLC Fotagliptin benzoate | 1403496-40-1 | 99.2% | 464.49 | C24H25FN6O3 | 25MG
Fotagliptin benzoate is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor provided as a benzoate salt for research use. It is intended for studies of type 2 diabetes mellitus and is supplied in analytical/research grade formulations with reported high purity and available package sizes suitable for both in vitro and in vivo experiments.
- Dipeptidyl peptidase-4 (DPP-4) inhibitor (IC50 = 2.27 nM).
- High purity (99.2%).
- Molecular weight 464.49 g/mol.
- Molecular formula C24H25FN6O3.
- Available in multiple package sizes, including 25 mg.
- Suitable for in vitro and in vivo studies.
- Reported safety data available from rat and dog studies.
Selleck Chemical LLC FK-3311 S2595-5mg
FK-3311 (COX-2 Inhibitor V) is a selective cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of TxA2
Selleck Chemical LLC 7-Methoxycoumarin S5163-25mg
7-Methoxycoumarin (Herniarine) also known as Herniarin is a methoxy derivative of coumarin and substrate for dealkylase It has been used in the synthesis of anti-first-pass effect compounds and detergents
Selleck Chemical LLC Chrysin S2281-1g
Chrysin (NSC 407436) is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea)
Selleck Chemical LLC Rutin S2350-1g
Rutin (Rutoside) a flavonol glycoside found in many plants including buckwheat tobacco forsythia hydrangea viola etc which possesses healthy effects for human
Selleck Chemical LLC Tangeretin S2363-5mg
Tangeretin (Tangeritin) a natural polymethoxylated flavone concentrated in the peel of citrus fruits an inhibitor of Notch1 is known to have antiproliferative antiinvasive antimetastatic and antioxidant activities
Selleck Chemical LLC Acacetin S5318-25mg
Acacetin (Linarigenin 5 7-dihydroxy-4 -methoxyflavone 4 -Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer anti-mutagenic anti-inflammatory and anti-peroxidative effects
Selleck Chemical LLC Nobiletin S2333-5mg
Nobiletin a citrus flavonoid isolated from citrus peels like in tangerine which has anti-inflammatory and anti-tumor activities
Medchemexpress LLC 2-phenylpropionic acid | 492-37-5 | MFCD00002650 | 99.7% | 150.18 g/mol | C9H10O2 | 5 G
2-Phenylpropionic acid is a small-molecule organic acid used as an analytical standard and research intermediate. It is a colorless to light-yellow liquid (C9H10O2) with a molecular weight of 150.18 g/mol and documented physical properties, making it suitable for analytical and synthetic applications.
Medchemexpress LLC Fotagliptin benzoate | 1403496-40-1 | 99.2% | 464.49 g·mol⁻1 | C24H25FN6O3 | 5MG
Fotagliptin benzoate is a research-grade dipeptidyl peptidase-4 (DPP-4) inhibitor provided as the benzoate salt for preclinical and biochemical studies related to type 2 diabetes research. It is supplied as a solid powder and in small analytical vial sizes for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin >=99%, FCC, FG | 119-84-6 | MFCD00006881 | 1KG
Dihydrocoumarin >=99%, FCC, FG | Purity: >=99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 | 1KG
